Reduces the contraction of muscle cells (innovative in vitro model)
Anti-wrinkle activity (in vivo topical test on crow’s foot area)
Biotransformation of peptides from Hibiscus seeds

A Mild and Safe Alternative to Drastic Procedures

There are 2 main mechanisms in wrinkles apparition: biological ones (ageing of cells, oxidation or glycation of macromolecules…), and mechanical ones, when face muscles are involved.

Facial muscles are responsible for the formation of dynamic wrinkles: horizontal and vertical frown lines across the forehead, crow’s feet around the eye and "naso-labial" line around the mouth.

A recent evolution of the cosmetic industry has offered to prevent these dynamic wrinkles by inhibiting facial muscle contraction.

To answer the need for a topical, gentle alternative to drastic procedures, Laboratoires Sérbiologiques have developed MYOXINOL™ LS 9736, with a targeted activity against expression lines.

MYOXINOL™ actually goes further, as its efficacy against mechanical parameters of ageing in complemented by a biological one, offering a comprehensive anti-wrinkle approach (patented).

MYOXINOL™ is a complex of oligopeptides obtained by biotransformation of native proteins from the seeds of Hibiscus esculentus L. (okra).

Efficacy tests
Inhibition of muscle cells contraction, in vitro 

MYOXINOL™ LS 9736 significantly reduces muscle cells contraction.
This effect is longer lasting then the reference, completely reversible after 24 hours, yet providing evidence of the harmlessness of MYOXINOL™ on the long term.

MYOXINOL™ inhibits the mechanical factor responsible for expression lines apparition.

Complementary tests: 
Anti-oxidant effect, in vitro.
Anti-wrinkle activity (clinical test), topical reduction:
26% wrinkle reduction (mean value versus placebo). 
Cosmetic application
Facial anti-age
Topical answer to smooth expression lines.
Substitution or spacing-out of drastic procedures.
Techincal data
INCI Name : Hydrolyzed Hibiscus Esculentus Extract (and) Dextrin.
Dose of use : 0.5 to 2%
Aspect  : fine powder, beige to pale yellow, of characteristic odor.
Solubility : MYOXINOL™ is soluble in water, insoluble in oils and fats.
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